Junior NTR is the grandson of veteran actor and former Chief Minister of Andhra Pradesh N.T. Rama Rao and the son of actor and Member of Parliament Nandamuri Harikrishna.N.T.R. marked his debut in Telugu cinema as a child actor in Brahmarshi Viswamitra (1991).In 2001 he starred in a lead role with Ninnu Chudalani.He then acted in many successful hits like Aadi, Simhadri, Rakhi, Yamadonga, Adhurs, Brindavanam, Oosaravelli, and Dammu which established him as one of the leading actors in Telugu cinema.
N.T.R. has won two Andhra Pradesh state Nandi Awards, one Filmfare Best Telugu Actor Award, three CineMAA Awards.